RAS PresidiumДоклады Российской академии наук. Химия, науки о материалах Doklady Chemistry

  • ISSN (Print) 2686-9535
  • ISSN (Online) 3034-5111

SYNTHESIS AND ANTIVIRAL ACTIVITY OF COPOLYMERS OF OXYCINNAMIC ACID WITH N-VINYLAMIDES

PII
10.31857/S2686953523600320-1
DOI
10.31857/S2686953523600320
Publication type
Status
Published
Authors
Volume/ Edition
Volume 513 / Issue number 1
Pages
77-81
Abstract
Radical copolymerization of coumarin with N-vinylamides (N‑vinylpyrrolidone, N-methyl-N-vinylacetamide, N-vinylformamide) was used to prepare copolymers of various natures and varied molecular masses. After the subsequent reactions in polymer chains, water-soluble copolymers of salts of oxycinnamic acid and its hydrazides were obtained. The synthesized copolymers of salts and hydrazides of oxycinnamic acid with N-vinylamides have low cytotoxicity and demonstrate the pronounced antiviral activity against human respiratory syncytial virus (strain A2).
Keywords
кумарин сополимеры оксикоричной кислоты <i>N-</i>виниламиды противовирусная активность гидразиды оксикоричной кислоты
Date of publication
18.09.2025
Year of publication
2025
Number of purchasers
0
Views
6

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