RAS PresidiumДоклады Российской академии наук. Химия, науки о материалах Doklady Chemistry

  • ISSN (Print) 2686-9535
  • ISSN (Online) 3034-5111

CITRUS PECTIN COMPLEXES WITH NIFEDIPINE: PREPARATION AND PHYSICOCHEMICAL PROPERTIES

PII
10.31857/S2686953523700176-1
DOI
10.31857/S2686953523700176
Publication type
Status
Published
Authors
Volume/ Edition
Volume 508 / Issue number 1
Pages
103-110
Abstract
The formation of stable complexes of pectin polysaccharides with the hypotensive drug “Nifedipine” was confirmed by IR and UV spectroscopy, their stoichiometry was determined and the conditions of their production were optimized. Peculiarities of thermal decomposition of pectin and synthesized complexes with nifedipine were studied by TGA/DSC method. The results obtained are a scientific basis for the creation of a new water-soluble non-toxic dosage form of nifedipine, which will significantly expand the use of the drug in medicine.
Keywords
цитрусовый пектин нифедипин комплексообразование комплексы ТГА/ДСК
Date of publication
18.09.2025
Year of publication
2025
Number of purchasers
0
Views
5

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